Gynaeco oncology trials

Contact: [email protected]

* Studie on hold

TitleTumor TypeLineStudy information
RAINBO-greenEndometrial dMMRAdjAdjuvant radiotherapy + durvalumab q4w x 13 (experimental arm) vs. adjuvant radiotherapy +/- chemotherapy (standard arm)
R4018-ONC-1721*Ovarian (epithelial)>1LREGN4018 IV QW +/- cemiplimab IV Q3W ; at least 1 prior platinum line for which progression
CIP-S25470MultipleCancer during pregnancy and in first 5 years after delivery
CIP-S62388MultipleCancer during pregnancy
VS-6766-301 (Verastem)Low grade ovarian>1LAvutometinib (VS-6766) + Defactinib (VS-6063) vs investigator choice; currently only recruiting KRAS mutant patients
TORL123-002 (CATALINA-2)Ovarian (epithelial)1-3LEvaluating different doses of TORL-123 IV Q3W; first prescreening for Claudin-6 expression (has to be positive)
MK2870-036 (Trofuse-036)m+ Cervix (PD-L1 CPS >=1)Part 1: maintenance after 1L
Part 2: 1L
Sacituzumab Tirumotecan (MK-2870) Q2W in Combination With Pembrolizumab Q6W With or Without Bevacizumab Q3W Compared With Standard of Care

Research Team